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Effect of lamictal on organic cationic transporter 2 substrates.

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Initial doses of LAMICTAL should be based on patientsAED regimensreduced maintenance doses may be effective for patients with significant renal impairmentFew patients with severe renal impairment have been evaluated during chronic treatment with lamotrigineBecause there is inadequate experience in this populationLAMICTAL should be used with caution in these patientssee DOSAGE AND ADMINISTRATION

Lamotrigine is an inhibitor of renal tubular secretion via organic cationic transporter 2OCT2proteinssee CLINICAL PHARMACOLOGYThis may result in increased plasma levels of certain drugs that are substantially excreted via this routeCoadministration of LAMICTAL with OCT2 substrates with a narrow therapeutic indexe.gdofetilideis not recommended.

To avoid an increased risk of rashthe recommended initial dose and subsequent dose escalations of LAMICTAL should not be exceededsee BOXED WARNING

This Medication Guide order doxycycline, order zithromax. summarizes the most important information about LAMICTALIf you would like more informationtalk with your healthcare providerYou can ask your healthcare provider or pharmacist for information about LAMICTAL that is written for healthcare professionals.

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la mayor a de los exantemas son leves y autolimitados; sin embargo, tambi n se han reportado exantemas graves que requieren hospitalizaci n y descontinuaci n de lamictal dispersable.