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If you are also taking colesevelamtake glyburide/metformin at least 4 hours before colesevelam.

Sulfonylurea drugs are extensively bound to serum proteinsDisplacement from protein binding sites by other drugs may lead to enhanced hypoglycemic actionIn vitrothe protein binding exhibited by glyburide is predominantly non-ionicwhereas that of other sulfonylureaschlorpropamidetolbutamidetolazamideis predominantly ionicAcidic drugssuch as phenylbutazonewarfarinand salicylatesdisplace the ionic-binding sulfonylureas from serum proteins to a far purchase sildenafil, purchase lioresal. greater extent than the non-ionic binding glyburideIt has not been shown that this difference in protein binding results in fewer drug-drug interactions with glyburide tablets in clinical use.

Initial and periodic monitoring of hematologic parameterse.ghemoglobin/hematocrit and red blood cell indicesand renal functionserum creatinineshould be performedat least on an annual basisWhile megaloblastic anemia has rarely been seen with metformin therapyif this is suspectedvitamin B 12 deficiency should be excluded.

If you need to have any type of x-ray or CT scan using a dye that is injected into your veinsyou will need to temporarily stop taking Glucovance.

Learn about type 2 diabetes warning signssymptomsdiagnosisand treatment optionsRead how diet and exercise can help manage.

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