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In vitro studies suggest the importance of lipitor metabolism by cytochrome p450 3a4, consistent with increased plasma concentrations of lipitor in humans following co-administration with erythromycin, a known inhibitor of this isozyme see drug interactions .

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Erythromycin may cause a condition that affects the heart rhythmQT prolongationQT prolongation can rarely cause seriousrarely fatalfast/irregular heartbeat and other symptomssuch as severe dizzinessfaintingthat need medical attention right away.

Serious side effects may be more likely in older adultsincluding hearing lossor a life-threatening fast heart rate.

If you are taking this medication to prevent certain bacterial infectionstake it exactly as directed by your doctorDo not stop taking the medication without your doctor’s approval.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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use with cyp3a4 inhibitorscaution should be exercised when prescribing cialis to patients using potent cyp3a4 inhibitors ritonavir, saquinavir, ketoconazole, itraconazole, and erythromycin , as increased tadalafil exposure auc has been observed if the medicinal products are combined see section 4.