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Table 3Treatment-Emergent Adverse ReactionsIncidence of 2or More and Greater than Placebo in MDD and GAD Placebo-Controlled Trials a,b.

Table 5Mean Change in ASEX Scores by Gender in MDD Placebo-Controlled Trials.

The most common side effects of duloxetine are nauseadry mouthconstipationdiarrheafatiguedifficulty sleepingand dizzinessIncreased blood pressure can occur and should be monitoredSeizures have been reportedSexual dysfunctiondecreased sex drive and delayed orgasm and ejaculationhas been associated with duloxetine.

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cymbalta is indicated for the treatment of major depressive disorder, diabetic neuropathy, generalized anxiety disorder, and fibromyalgia, but may also be prescribed for other conditions.